Package index • adagraph

All functions

adagraph_design(): Make a new (generic) trial design

cer_adapt(): Adapt the trial design after the interim test

cer_adapt_bounds(): Adjust bounds after changing some design parameters

cer_alt_drop_hypotheses(): Adapt a cer design by dropping hypotheses, with a simplified strategy for redistributing weights

cer_design(): Make a new CER trial design

cer_drop_hypotheses(): Adapt a cer design by dropping hypotheses

cer_final_test(): Test a cer design for early rejection of hypotheses and calculate the CER for adaptions

cer_interim_test(): Test a cer design for early rejection of hypotheses and calculate the CER for adaptions

cer_prep_bounds(): Calculate bounds for preplanned test

get_cer(): Get the Conditional Error Rate for a intersection of hypotheses

get_data_gen(): Get a data generating function for simulating a trial

get_data_gen_2(): Get a data generating function for simulating the second stage of a trial

get_t(): Get the time fractions for given sample sizes

multiarm_cer_design(): Make a new multiarm CER trial design

multiarm_drop_arms(): Drop arm from a multiarm design

redistribute_n(): Get the amount of people for each hypotheses in the 2. stage of a trial assuming a fixed population

sim_trial(): Run a series of simulated trials according to a specified design